Article
Cytochrome P450 II D6 gene polymorphisms and the neuroleptic-induced extrapyramidal symptoms in Japanese schizophrenic patients.
Psychiatric genetics - 1 Sept 2003
Inada Toshiya, Senoo Hisashi, Iijima Yoshimi, Yamauchi Tadamitsu, Yagi Gohei
Abstract excerpt
OBJECTIVE: The purpose of this study was to examine whether the neuroleptic-induced extrapyramidal symptoms are associated with the CYP2D6 activity. METHODS: The CYP2D6 gene polymorphisms (CYP2D6*2, CYP2D6*3, CYP2D6*4, CYP2D6*10, and CYP2D6*12) were genotyped in 196 normal controls and 320 schizo...
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