Article
Antipsychotic-induced extrapyramidal syndromes and cytochrome P450 2D6 genotype: a case-control study.
Pharmacogenetics - 1 Apr 2002
Schillevoort Igor, de Boer Anthonius, van der Weide Jan, Steijns Linda S W, Roos Raymund A C, Jansen Paul A F, Leufkens Hubert G M
Abstract excerpt
To study the association between polymorphism of the cytochrome P450 2D6 gene (CYP2D6) and the risk of antipsychotic-induced extrapyramidal syndromes, as measured by the use of antiparkinsonian medication. Data for this case-control study were obtained from a psychiatric hospital where newly admitted patients are routinely screened for several CYP2D6 mutant alleles. Cases were patients prescribed antiparkinsonian...
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