Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence.

doi:10.1002/mgg3.1789

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Article

Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence.

Molecular genetics & genomic medicine - 1 Oct 2021

Liu Huan, Zhang Wei, Deng Xiao-Dong, Ma Ying, Liu Yun

Abstract excerpt

BACKGROUND: The quinone oxidoreductase 1 (NQO1) gene was involved in the pathophysiological process of illicit drugs abuse, and its polymorphisms might be associated with methamphetamine (METH) dependence susceptibility. The purpose of this study was to examine the NQO1 mRNA and protein levels and to analyze the 609C/T polymorphism (rs1800566) between METH-dependent patients and controls. METHODS: A total of...

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PMID: 34467676
DOI: 10.1002/mgg3.1789
PMCID: PMC8580086

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