Article
Association of NQO1 levels and its genetic polymorphism with susceptibility to methamphetamine dependence.
Molecular genetics & genomic medicine - 1 Oct 2021
Liu Huan, Zhang Wei, Deng Xiao-Dong, Ma Ying, Liu Yun
Abstract excerpt
BACKGROUND: The quinone oxidoreductase 1 (NQO1) gene was involved in the pathophysiological process of illicit drugs abuse, and its polymorphisms might be associated with methamphetamine (METH) dependence susceptibility. The purpose of this study was to examine the NQO1 mRNA and protein levels an...
Topics
- Adult
- Alleles
- Amphetamine-Related Disorders
- Biomarkers
- Case-Control Studies
- Female
- Gene Expression
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- NAD(P)H Dehydrogenase (Quinone)
- Odds Ratio
- Polymorphism, Single Nucleotide
- Symptom Assessment