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Article

Role of surfactant protein-A in nitric oxide production and mycoplasma killing in congenic C57BL/6 mice.

American journal of respiratory cell and molecular biology - 1 Mar 2004

Hickman-Davis Judy M, Gibbs-Erwin Julie, Lindsey J Russell, Matalon Sadis

Abstract excerpt

We generated congenic surfactant protein A (SP-A)-deficient (SP-A[-/-]) mice on the mycoplasma resistant C57BL/6 background (B6.SP-A[-/-]) and characterized their response to mycoplasma infection in comparison to C57BL/6 (B6) mice. B6.SP-A(-/-) mice infected with 10(6) colony-forming units (cfu) of Mycoplasma pulmonis had significantly higher bacterial lung loads than B6 mice at 72 h postinfection (p.i.). At the...

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Identifiers

PMID: 12959946
DOI: 10.1165/rcmb.2003-0246OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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