Article
Attenuation of in vitro host-pathogen interactions in quinolone-resistant Salmonella Typhi mutants.
The Journal of antimicrobial chemotherapy - 1 Jan 2016
Ballesté-Delpierre Clara, Fàbrega Anna, Ferrer-Navarro Mario, Mathur Ramkumar, Ghosh Sankar, Vila Jordi
Abstract excerpt
OBJECTIVES: The relationship between quinolone resistance acquisition and invasion impairment has been studied in some Salmonella enterica serovars. However, little information has been reported regarding the invasive human-restricted pathogen Salmonella Typhi. The aim of this study was to investigate the molecular mechanisms of quinolone resistance acquisition and its impact on virulence in this serovar....
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