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Article

A soluble peripherin/Rds C-terminal polypeptide promotes membrane fusion and changes conformation upon membrane association.

Experimental eye research - 1 Oct 2003

Boesze-Battaglia Kathleen, Goldberg Andrew F X, Dispoto Janice, Katragadda Madan, Cesarone Gregory, Albert Arlene D

Abstract excerpt

Photoreceptor rod cells contain a unique tetraspanin fusion protein known as peripherin/rds. This protein is important in membrane fusion events hypothesized to be essential to disk membrane morphogenesis and disk shedding. In vivo and in vitro fusogenic activity has been mapped to the C-terminal domain of peripherin/rds. Moreover, a fusion peptide domain localized to a 15 amino acid long region (residues...

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Identifiers

PMID: 12957149
DOI: 10.1016/s0014-4835(03)00151-9
PMCID: PMC4732724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A soluble peripherin/Rds C-terminal polypeptide promotes membrane fusion and changes conformation upon membrane association.PMID 12957149Read ↗

Deletional analysis of the rod photoreceptor cell peripherin/RDS carboxy-terminal region.Semantic proximity Read ↗

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Peripherin/rds Influences Membrane Vesicle MorphologySemantic proximity Read ↗

Role of the Second Intradiscal Loop of Peripherin/<i>rds </i>in Homo and Hetero AssociationsSemantic proximity Read ↗

Folding and subunit assembly of photoreceptor peripherin/rds is mediated by determinants within the extracellular/intradiskal EC2 domain: implications for heterogeneous molecular pathologies.Semantic proximity Read ↗

An intramembrane glutamic acid governs peripherin/rds function for photoreceptor disk morphogenesis.Semantic proximity Read ↗

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