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Article

A sensitive method for detecting variation in copy numbers of duplicated genes.

Genome research - 1 Sept 2003

Pielberg Gerli, Day Andy E, Plastow Graham S, Andersson Leif

Abstract excerpt

Gene duplications are common in the vertebrate genome, and duplicated loci often show a variation in copy number that may have important phenotypic effects. Here we describe a powerful method for quantification of duplicated copies based on pyrosequencing. A reliable quantification was obtained by amplification of the duplication break-point and a corresponding nonduplicated sequence in a competitive PCR assay. A...

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Identifiers

PMID: 12952884
DOI: 10.1101/gr.1188203
PMCID: PMC403722

Genes

KIT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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