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Article

A large duplication associated with dominant white color in pigs originated by homologous recombination between LINE elements flanking KIT.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2002

Giuffra Elisabetta, Törnsten Anna, Marklund Stefan, Bongcam-Rudloff Erik, Chardon Patrick, Kijas James M H, Anderson Susan I, Archibald Alan L, Andersson Leif

Abstract excerpt

The Dominant White (I/KIT) locus is one of the major coat color loci in the pig. Previous studies showed that the Dominant White (I) and Patch (IP) alleles are both associated with a duplication including the entire KIT coding sequence. We have now constructed a BAC contig spanning the three closely linked tyrosine kinase receptor genes PDGFRA-KIT-KDR. The size of the duplication was estimated at about 450 kb and...

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Source

Identifiers

PMID: 12420135
DOI: 10.1007/s00335-002-2184-5

Genes

KIT
KDR
PDGFRA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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