Article
Porcine endogenous retrovirus copy number in different pig breeds is not related to genetic diversity.
Zoonoses and public health - 1 Sept 2012
Quereda J J, Herrero-Medrano J M, Abellaneda J M, García-Nicolás O, Martínez-Alarcón L, Pallarés F J, Ramírez P, Muñoz A, Ramis G
Abstract excerpt
The risk of zoonoses is a major obstacle to xenotransplantation. Porcine endogenous retrovirus (PERV) poses a potential risk of zoonotic infection, and its control is a prerequisite for the development of clinical xenotransplantation. The copy number of PERV varies among different breeds, and it has been suggested that the PERV integrations number is increased by inbreeding. The purpose of this study was (i) to...
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