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Article

Porcine endogenous retroviruses: Quantification of the copy number in cell lines, pig breeds, and organs

1 Jul 2018

Abstract excerpt

BACKGROUND: Porcine endogenous retroviruses (PERVs) may pose a risk of xenotransplantation using porcine cells, tissues, or organs. PERVs are integrated in the genome of all pigs, and some can infect certain human cells. The copy number of PERVs in different pig breeds has been determined by using different methods, with varying results. METHODS: To determine the PERV copy number in pig cell lines and in animals,...

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PMID: 30264881
DOI: 10.1111/xen.12445

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