Article
Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 1996
Johansson Moller M, Chaudhary R, Hellmén E, Höyheim B, Chowdhary B, Andersson L
Abstract excerpt
Comparative mapping data suggested that the dominant white coat color in pigs may be due to a mutation in KIT which encodes the mast/stem cell growth factor receptor. We report here that dominant white pigs lack melanocytes in the skin, as would be anticipated for a KIT mutation. We found a complete association between the dominant white mutation and a duplication of the KIT gene, or part of it, in samples of...
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