Article
Pigs with the dominant white coat color phenotype carry a duplication of the KIT gene encoding the mast/stem cell growth factor receptor.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 1996
Johansson Moller M, Chaudhary R, Hellmén E, Höyheim B, Chowdhary B, Andersson L
Abstract excerpt
Comparative mapping data suggested that the dominant white coat color in pigs may be due to a mutation in KIT which encodes the mast/stem cell growth factor receptor. We report here that dominant white pigs lack melanocytes in the skin, as would be anticipated for a KIT mutation. We found a compl...
Topics
- Animals
- Base Sequence
- Chromosome Mapping
- Chromosomes, Human, Pair 4
- DNA Primers
- Exons
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Hair Color
- Humans
- In Situ Hybridization, Fluorescence
- Molecular Sequence Data
- Phenotype
- Polymerase Chain Reaction