Article
Global haplotype diversity in the human insulin gene region.
Genome research - 1 Sept 2003
Stead John D H, Hurles Matthew E, Jeffreys Alec J
Abstract excerpt
The insulin minisatellite (INS VNTR) has been intensively analyzed due to its associations with diseases including diabetes. We have previously used patterns of variant repeat distribution in the minisatellite to demonstrate that genetic diversity is unusually great in Africans compared to non-Africans. Here we analyzed variation at 56 single nucleotide polymorphisms (SNPs) flanking the minisatellite in...
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