Article
Association study between late-onset Alzheimer's disease and the transferrin gene polymorphisms in Chinese.
Neuroscience letters - 9 Oct 2003
Zhang Peng, Yang Ze, Zhang Chuanfang, Lu Zeping, Shi Xiaohong, Zheng Weidong, Wan Chunling, Zhang Duanyang, Zheng Chenguang, Li Shu, Jin Feng, Wang Li
Abstract excerpt
To investigate the possible involvement of the transferrin (TF) gene polymorphism in the manifestation of Alzheimer's disease (AD), we analyzed the TF and apolipoprotein E (APOE) genotypes of 67 sporadic late-onset AD patients and 131 normal elderly controls in the Chinese population. Our data showed that the TF C1 homozygosity carriers had an increased risk of AD in subjects > or =75 years of age, showing that...
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