Article
Genetic abnormalities in marginal zone B-cell lymphoma.
Hematological oncology - 1 Mar 2000
Dierlamm J, Wlodarska I, Michaux L, Stefanova M, Hinz K, Van Den Berghe H, Hagemeijer A, Hossfeld D K
Abstract excerpt
Marginal zone B-cell lymphoma (MZBCL) including extranodal mucosa-associated lymphoid tissue (MALT)-type lymphoma, nodal, and splenic MZBCL represents a distinct subtype of B-non-Hodgkin's lymphoma. Recently, important progress in the elucidation of the genetic mechanisms underlying the pathogenesis and disease progression of these lymphomas has been made. The API2 gene, an inhibitor of apoptosis, and the novel...
Topics
- Chromosome Aberrations
- Chromosomes, Human, Pair 1
- Chromosomes, Human, Pair 11
- Chromosomes, Human, Pair 14
- Chromosomes, Human, Pair 18
- Humans
- Lymphoma, B-Cell
- Lymphoma, B-Cell, Marginal Zone
- Mutation
- Proto-Oncogene Mas
- Translocation, Genetic
