Primary Cutaneous Marginal Zone B-cell Lymphoma May Exhibit Both the t(14;18)(q32;q21) IGH/BCL2 and the t(14;18)(q32;q21) IGH/MALT1 Translocation: An Indicator for Clonal Transformation Towards Higher-Grade B-cell Lymphoma?

Abstract excerpt

Primary cutaneous marginal zone B-cell lymphoma (PCMZL) is a recently proposed entity and constitutes the cutaneous counterpart of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT). The t(14;18)(q32;q21) involving the IGH and the MALT1 gene has previously been described in PCMZL, whereas the t(14;18)(q32;q21) IGH/BCL2 seems to be restricted to follicular lymphoma and diffuse...

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