Article
Met signaling is required for recruitment of motor neurons to PEA3-positive motor pools.
Neuron - 28 Aug 2003
Helmbacher Françoise, Dessaud Eric, Arber Silvia, deLapeyrière Odile, Henderson Christopher E, Klein Rüdiger, Maina Flavio
Abstract excerpt
Motor neurons in the spinal cord are grouped into motor pools, each of which innervates a single muscle. The ETS transcription factor PEA3 is a marker of a few such motor pools. Here, we show that pea3 is first induced by GDNF in a caudal subset of the motor neurons that will constitute the pea3+...
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