Article
Urokinase gene 3'-UTR T/C polymorphism is associated with urolithiasis.
Urology - 1 Mar 2002
Tsai Fuu-Jen, Lin Cheng-Chieh, Lu Hsueh-Fu, Chen Huey-Yi, Chen Wen-Chi
Abstract excerpt
OBJECTIVES: To study single nucleotide polymorphisms to investigate the possibility that urokinase is involved in the formation of urolithiasis, which, although lacking in genetic evidence, has been previously proposed. METHODS: A total of 153 patients with recurrent calcium stones and 105 controls were studied. Polymerase chain reaction-based restriction analysis was used to identify the C/T polymorphism of the...
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