Article
Association between environmental tobacco smoke exposure and lung cancer susceptibility: modification by antioxidant enzyme genetic polymorphisms.
Molecular diagnosis & therapy - 1 Feb 2014
Fathy Mona, Hamed Mai, Youssif Omnia, Fawzy Nahla, Ashour Wafa
Abstract excerpt
BACKGROUND: Environmental tobacco smoke (ETS) is the primary etiologic factor responsible for lung cancer. However, only 10-15 % of smokers develop lung cancer, suggesting a genetic role in modifying individual susceptibility to lung cancer. Antioxidant enzymes and genetic polymorphisms should be considered. AIM: The present study aimed to evaluate the role of antioxidant enzyme activity and genetic polymorphisms...
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