Article
Plasma membrane calcium ATPase overexpression in arterial smooth muscle increases vasomotor responsiveness and blood pressure.
Circulation research - 3 Oct 2003
Gros Robert, Afroze Talat, You Xiao-Mang, Kabir Golam, Van Wert Ryan, Kalair Waseem, Hoque Abunasr E, Mungrue Imran N, Husain Mansoor
Abstract excerpt
In vascular smooth muscle cells (SMCs), several mechanisms act in concert to regulate the intracellular calcium concentration [Ca2+]i, which may in turn affect vascular tone. One such mechanism is the extrusion of Ca2+ by the plasma membrane calcium ATPase (PMCA). To address, in particular, the r...
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