Article
Cooperative activities of drosophila DE-cadherin and DN-cadherin regulate the cell motility process of ommatidial rotation.
Development (Cambridge, England) - 1 Sept 2006
Mirkovic Ivana, Mlodzik Marek
Abstract excerpt
Ommatidial rotation is a cell motility read-out of planar cell polarity (PCP) signaling in the Drosophila eye. Although the signaling aspects of PCP establishment are beginning to be unraveled, the mechanistic aspects of the associated ommatidial rotation process remain unknown. Here, we demonstrate that the Drosophila DE- and DN-cadherins have opposing effects on rotation. DE-cadherin promotes rotation, as...
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