Article
Identification of genes differentially expressed in C6 glioma cells transfected with connexin43.
Brain research. Brain research reviews - 1 Apr 2000
Naus C C, Bond S L, Bechberger J F, Rushlow W
Abstract excerpt
Astrocytes are characterized by extensive gap junctional intercellular communication (GJIC) mediated primarily by channels composed of connexin43. In contrast, C6 glioma cells are deficient in connexin expression and gap junctional communication. Transfection of these glioma cells with connexin cDNAs results in changes in cellular phenotype following increased GJIC. Specifically, connexin expression correlates...
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