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Article

In vitro generation of Salmonella spp. mutants following repeated exposure to beta-lactam antibiotics.

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy - 1 Apr 2006

Cebrián Laura, Rodríguez Juan Carlos, Escribano Isabel, Royo Gloria

Abstract excerpt

Beta-lactams are a group of drugs considered to be the treatment of choice in cases of salmonellosis, although many isolates that are clinically resistant to these compounds have been reported. We developed an in vitro model to determine the dynamics of the generation of resistant mutants following repeated exposure to these drugs. All the isolates exposed repeatedly to amoxicillin and cefotaxime exhibit a...

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Source

Identifiers

PMID: 16648947
DOI: 10.1007/s10156-005-0430-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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