Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Beta-arrestin-2 regulates the development of allergic asthma.

The Journal of clinical investigation - 1 Aug 2003

Walker Julia K L, Fong Alan M, Lawson Barbara L, Savov Jordan D, Patel Dhavalkumar D, Schwartz David A, Lefkowitz Robert J

Abstract excerpt

Asthma is a chronic inflammatory disorder of the airways that is coordinated by Th2 cells in both human asthmatics and animal models of allergic asthma. Migration of Th2 cells to the lung is key to their inflammatory function and is regulated in large part by chemokine receptors, members of the s...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arrestins
Share to beta-Arrestin 2
Share to beta-Arrestins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD3 Complex

Share to Chemotaxis

Share to Endotoxins

Share to Methacholine Chloride

Share to Th2 Cells

Source

Open in PubMed Open full text

Identifiers

PMID: 12925697
DOI: 10.1172/JCI17265
PMCID: PMC171386

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12925697-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Beta-arrestin-2 regulates the development of allergic asthma.PMID 12925697Read ↗

β-Arrestin-2–Dependent Signaling Promotes CCR4–mediated Chemotaxis of Murine T-Helper Type 2 CellsSemantic proximity Read ↗

β-Arrestins 1 and 2 are critical regulators of inflammationSemantic proximity Read ↗

Allergic asthma is distinguished by sensitivity of allergen-specific CD4+ T cells and airway structural cells to type 2 inflammation.Semantic proximity Read ↗

Multifaceted role of β-arrestins in inflammation and diseaseSemantic proximity Read ↗

Absence of alpha 4 but not beta 2 integrins restrains development of chronic allergic asthma using mouse genetic models.Semantic proximity Read ↗

Phosphodiesterase 4 Inhibitors Attenuate the Asthma Phenotype Produced by β2-Adrenoceptor Agonists in Phenylethanolamine N-Methyltransferase-Knockout Mice.Semantic proximity Read ↗

Activation and nuclear translocation of ERK1/2 by the formyl peptide receptor is regulated by G protein and is not dependent on beta-arrestin translocation or receptor endocytosis.Semantic proximity Read ↗

Distinct and Shared Roles of β-Arrestin-1 and β-Arrestin-2 on the Regulation of C3a Receptor Signaling in Human Mast CellsSemantic proximity Read ↗

Identification of beta-arrestin2 as a G protein-coupled receptor-stimulated regulator of NF-kappaB pathways.Semantic proximity Read ↗

Beta2-adrenoceptor signaling is required for the development of an asthma phenotype in a murine model.Semantic proximity Read ↗

P2rx4 deficiency in mice alleviates allergen-induced airway inflammation.Semantic proximity Read ↗

Role for β-arrestin in mediating paradoxical β2AR and PAR2 signaling in asthmaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.