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Article

Shortening adenovirus type 5 fiber shaft decreases the efficiency of postbinding steps in CAR-expressing and nonexpressing cells.

Virology - 1 Aug 2003

Ambriović-Ristov Andreja, Mercier Stephanie, Eloit Marc

Abstract excerpt

The coxsackie B virus and adenovirus receptor (CAR) functions as an attachment receptor for multiple adenovirus serotypes. It has been shown that apart from virus-cellular receptor interactions, the fiber shaft length also influences viral tropism. We therefore generated Ad5FbDelta639 virus with 8beta-repeats in the shaft, instead of the 22beta-repeats present in the wild-type. Here, we show that the extent of...

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PMID: 12919747
DOI: 10.1016/s0042-6822(03)00238-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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