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Fiber1, but not fiber2, is the essential fiber gene for fowl adenovirus 4 (FAdV-4)

24 Feb 2021

Abstract excerpt

Fibre is the viral protein that mediates the attachment and infection of adenovirus to the host cell. Fowl adenovirus 4 (FAdV-4) possesses two different fibre trimers on each penton capsomere, and roles of the separate fibres remain elusive. Here, we attempted to investigate the function of FAdV-4 fibres by using reverse genetics approaches. Adenoviral plasmids carrying fiber1 or fiber2 mutant genes were...

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PMID: 33625352
DOI: 10.1099/jgv.0.001559

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