Limb-girdle muscular dystrophy is closely linked to the fibrillin locus on chromosome 15.

doi:10.3109/03008209309061962

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

Limb-girdle muscular dystrophy is closely linked to the fibrillin locus on chromosome 15.

Connective tissue research - 1 Jan 1993

Velinov M, Sarfarazi M, Young K, Hodes M E, Conneally P M, Jackson C E, Tsipouras P

Abstract excerpt

Limb-girdle Muscular Dystrophy (LGMD) is a rare form of muscular dystrophy inherited as an autosomal recessive trait. The LGMD locus was recently mapped to chromosome 15. We tested the hypothesis that fibrillin is a candidate in the etiology of the disorder by genetic linkage analysis. A large Am...

Topics

Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 15
DNA
Extremities
Female
Fibrillins
Gene Expression
Genes, Recessive
Genetic Linkage
Genotype
Humans
Male
Microfilament Proteins
Molecular Sequence Data
Muscular Dystrophies
Pedigree

Source

Open in PubMed

Identifiers

PMID: 8339542
DOI: 10.3109/03008209309061962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8339542-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics