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Article

Characterization of the p53 mutants ability to inhibit p73 beta transactivation using a yeast-based functional assay.

Oncogene - 14 Aug 2003

Monti Paola, Campomenosi Paola, Ciribilli Yari, Iannone Raffaella, Aprile Anna, Inga Alberto, Tada Mitsuhiro, Menichini Paola, Abbondandolo Angelo, Fronza Gilberto

Abstract excerpt

p53 is the most frequently altered tumor suppressor gene in a wide spectrum of human tumors. The large majority of p53 mutations observed in tumors are missense mutations. The p73 gene, encoding a protein with significant sequence similarity to p53, expresses multiple transcription-competent spli...

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PMID: 12917626
DOI: 10.1038/sj.onc.1206511

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12917626-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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