Article
Murid herpesvirus 4 strain 68 M2 protein is a B-cell-associated antigen important for latency but not lymphocytosis.
Journal of virology - 1 Sept 2003
Macrae Alastair I, Usherwood Edward J, Husain S Mazher, Flaño Emilio, Kim In-Jeong, Woodland David L, Nash Anthony A, Blackman Marcia A, Sample Jeffery T, Stewart James P
Abstract excerpt
This work describes analyses of the function of the murid herpesvirus 4 strain 68 (MHV-68) M2 gene. A frameshift mutation was made in the M2 open reading frame that caused premature termination of translation of M2 after amino acid residue 90. The M2 mutant showed no defect in productive replication in vitro or in lungs after infection of mice. Likewise, the characteristic transient increase in spleen cell...
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