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Article

Behavioural and anatomical effects of systemically administered leukemia inhibitory factor in the SOD1(G93A G1H) mouse model of familial amyotrophic lateral sclerosis.

Brain research - 22 Aug 2003

Azari Michael F, Lopes Elizabeth C, Stubna Chantelle, Turner Bradley J, Zang Dawei, Nicola Nicos A, Kurek John B, Cheema Surindar S

Abstract excerpt

We investigated the anatomical and behavioural effects of daily intraperitoneal injection of 25 microg/kg of LIF in the SOD1(G93A G1H) mouse model of familial ALS. We found some subtle beneficial behavioural changes in LIF treated mice. These included later onset of clinical disease in females as...

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Source

Identifiers

PMID: 12915243
DOI: 10.1016/s0006-8993(03)02989-5

Genes

LIF
SOD1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12915243-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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