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Article

Cyclooxygenase 2 expression and molecular alterations in Peutz-Jeghers hamartomas and carcinomas.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2003

De Leng Wendy W J, Westerman Anne Marie, Weterman Marian A J, De Rooij Felix W M, Dekken Hv Herman van, De Goeij Anton F P M, Gruber Stephen B, Wilson J H Paul, Offerhaus G Johan A, Giardiello Francis M, Keller Josbert J

Abstract excerpt

PURPOSE: Peutz-Jeghers syndrome (PJS) is a hamartomatous polyposis disorder with a high cancer risk. Debate exists about the premalignant potential of hamartomas. Also, treatment options other than surveillance are not available. Therefore, molecular alterations in hamartomas and PJS carcinomas w...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 12912958

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APC
STK11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12912958-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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