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Does endothelial nitric oxide synthase gene variation play a role in the occurrence of hypertension in pregnancy?

Hypertension in pregnancy - 1 Jan 2003

Grandone Elvira, Colaizzo Donatella, Martinelli Pasquale, Pavone Giuseppe, Errico Massimo, Vecchione Gennaro, Margaglione Maurizio

Abstract excerpt

OBJECTIVE: Nitric oxide is suggested to play a role in the development of preeclampsia. METHODS: We studied 61 patients with gestational hypertension (GH), 77 with GH and significant proteinuria (urine protein excretion > or = 300 mg/24 h), 82 with essential hypertension (EH) and 188 normotensive women with at least one normal pregnancy. MAIN OUTCOME MEASURE(S): A polymorphism within the constitutive endothelial...

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Identifiers

PMID: 12908999
DOI: 10.1081/PRG-120021061

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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