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Article

Genetic contribution of the endothelial constitutive nitric oxide synthase gene to plasma nitric oxide levels.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 1997

Wang X L, Mahaney M C, Sim A S, Wang J, Wang J, Blangero J, Almasy L, Badenhop R B, Wilcken D E

Abstract excerpt

Nitric oxide (NO) has an important physiological role in regulating vascular tone and is also relevant to many pathological processes including hypertension and atherosclerosis. Endothelial constitutive nitric oxide synthase (ecNOS) is the key enzyme in determining basal vascular wall NO production. We used a combination of maximum-likelihood-based statistical genetic methods to explore the contributions of the...

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PMID: 9409304
DOI: 10.1161/01.atv.17.11.3147

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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