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Article

pol gene sequence variation in Swedish HIV-2 patients failing antiretroviral therapy.

AIDS research and human retroviruses - 1 Jul 2003

Brandin Eleonor, Lindborg Lena, Gyllensten Katarina, Broström Christina, Hagberg Lars, Gisslen Magnus, Tuvesson Björn, Blaxhult Anders, Albert Jan

Abstract excerpt

There is limited knowledge about how to treat and interpret results from genotypic resistance assays in HIV-2 infection. Here, genetic variation in HIV-2 pol gene was studied in 20 of 23 known HIV-2 cases in Sweden. Five patients with signs of virological treatment failure were longitudinally studied. Clinical, virological and immunological data were collected and the protease (PR) and first half of the reverse...

Topics

Adolescent
Adult
Africa, Western
Amino Acid Sequence
Amino Acid Substitution
Anti-HIV Agents
Codon
Drug Resistance, Multiple, Viral
Evolution, Molecular
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Genes, pol

Genetic Variation

HIV Infections

HIV Protease Inhibitors

HIV-1

HIV-2

Humans

Lamivudine

Source

Identifiers

PMID: 12908931
DOI: 10.1089/088922203322230905

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-12908931-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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