Article
Diminished milk synthesis in upstream stimulatory factor 2 null mice is associated with decreased circulating oxytocin and decreased mammary gland expression of eukaryotic initiation factors 4E and 4G.
Molecular endocrinology (Baltimore, Md.) - 1 Nov 2003
Hadsell Darryl L, Bonnette Sharon, George Jessy, Torres Daniel, Klimentidis Yann, Klementidis Yann, Gao Shan, Haney Peter M, Summy-Long Joan, Soloff Melvyn S, Parlow Albert F, Sirito Mario, Sawadogo Michele
Abstract excerpt
Previous studies have suggested that upstream stimulatory factors (USFs) regulate genes involved with cell cycle progression. Because of the relationship of USFs to an important oncogene in breast cancer, c-myc, we chose to determine the importance of USF to normal mammary gland development in th...
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