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Article

Loss of USF2 promotes proliferation, migration and mitophagy in a redox-dependent manner

1 Oct 2020

Abstract excerpt

The upstream stimulatory factor 2 (USF2) is a transcription factor implicated in several cellular processes and among them, tumor development seems to stand out. However, the data with respect to the role of USF2 in tumor development are conflicting suggesting that it acts either as tumor promoter or suppressor. Here we show that absence of USF2 promotes proliferation and migration. Thereby, we reveal a...

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Identifiers

PMID: 33059314
DOI: 10.1016/j.redox.2020.101750

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