Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inherited disorders of cytokines.

Current opinion in pediatrics - 1 Dec 2004

Picard Capucine, Casanova Jean-Laurent

Abstract excerpt

PURPOSE OF REVIEW: Cytokines are soluble mediators involved in the development or function of the immune system. This paper reviews the literature on childhood-onset inherited disorders associated with impaired cytokine-mediated immunity. RECENT FINDINGS: Cytokine-mediated immunity defects can be classified into seven different groups: defects in the interleukin (IL)-7 receptor (IL7RA), in the common cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cytokines

Share to IFNGR1 gene

Share to Genetic Predisposition to Disease

Share to Immunologic Deficiency Syndromes

Share to Infant

Source

Identifiers

PMID: 15548928
DOI: 10.1097/01.mop.0000145919.92477.5f

Genes

CXCR4
IFNGR1
IFNGR2
IRAK4
JAK3
STAT1
TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inherited disorders of cytokines.PMID 15548928Read ↗

Inborn errors of IL-6 family cytokine responses.Semantic proximity Read ↗

Anti-cytokine autoantibodies and inborn errors of immunity.Semantic proximity Read ↗

Cytokine and cytokine receptor gene polymorphisms and their functionality.Semantic proximity Read ↗

Immune deficiencies due to defects in cytokine signaling.Semantic proximity Read ↗

Inborn errors of IL-12/23- and IFN-gamma-mediated immunity: molecular, cellular, and clinical features.Semantic proximity Read ↗

Congenital defects in the interferon-gamma/interleukin-12 pathway.Semantic proximity Read ↗

Signaling mechanisms of cytokine receptors and their perturbances in disease.Semantic proximity Read ↗

Cytokine gene polymorphisms and human autoimmune disease in the era of genome-wide association studies.Semantic proximity Read ↗

The Interleukin-7 Receptor Signaling Pathway and Its Perturbation in Immunodeficiency, Autoimmune Disease and Lymphoid Malignancy.Semantic proximity Read ↗

Diagnosis of defects in the type 1 cytokine pathway.Semantic proximity Read ↗

Mutations in genes required for T-cell development: IL7R, CD45, IL2RG, JAK3, RAG1, RAG2, ARTEMIS, and ADA and severe combined immunodeficiency: HuGE review.Semantic proximity Read ↗

Emerging Place of JAK Inhibitors in the Treatment of Inborn Errors of Immunity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.