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Article

Bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase): evidence for two distinct stages of methylation under single turnover conditions.

The Journal of biological chemistry - 24 Oct 2003

Malygin Ernst G, Lindstrom William M, Zinoviev Victor V, Evdokimov Alexey A, Schlagman Samuel L, Reich Norbert O, Hattman Stanley

Abstract excerpt

We compared the (pre)steady-state and single turnover methylation kinetics of bacteriophage T4Dam (DNA-(adenine-N6)-methyltransferase)-mediated methyl group transfer from S-adenosyl-l-methionine (AdoMet) to oligodeoxynucleotide duplexes containing a single recognition site (palindrome 5'-GATC/5'-GATC) or some modified variant. T4Dam-AdoMet functions as a monomer under steady-state conditions (enzyme/DNA << 1),...

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Identifiers

PMID: 12893823
DOI: 10.1074/jbc.M306397200

Genes

GATC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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