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Article

Transient Kinetics Define a Complete Kinetic Model for Protein Arginine Methyltransferase 1.

The Journal of biological chemistry - 23 Dec 2016

Hu Hao, Luo Cheng, Zheng Y George

Abstract excerpt

Protein arginine methyltransferases (PRMTs) are the enzymes responsible for posttranslational methylation of protein arginine residues in eukaryotic cells, particularly within the histone tails. A detailed mechanistic model of PRMT-catalyzed methylation is currently lacking, but it is essential for understanding the functions of PRMTs in various cellular pathways and for efficient design of PRMT inhibitors as...

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Source

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Identifiers

PMID: 27834681
DOI: 10.1074/jbc.M116.757625
PMCID: PMC5207181

Genes

PRMT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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