Article
Vascular endothelial growth factor gene-460 C/T polymorphism is a biomarker for prostate cancer.
Urology - 1 Aug 2003
Lin Cheng-Chieh, Wu Hsi-Chin, Tsai Fuu-Jen, Chen Huey-Yi, Chen Wen-Chi
Abstract excerpt
OBJECTIVES: To use the Bst U I polymorphism as a genetic marker in the search for the association between patients with prostate cancer and normal control subjects. The formation or progression of prostate cancer is presumed to be associated with a polymorphism of the vascular endothelial growth factor (VEGF) gene. The most frequently seen polymorphism is Bst U I (C to T) located at the -460th nucleotide upstream...
Topics
- Aged
- Aged, 80 and over
- Biomarkers, Tumor
- Cytosine
- Endothelial Growth Factors
- Genetic Markers
- Humans
- Intercellular Signaling Peptides and Proteins
- Lymphokines
- Male
- Middle Aged
