Article
T allele for VEGF gene-460 polymorphism at the 5'-untranslated region: association with a higher susceptibility to endometriosis.
The Journal of reproductive medicine - 1 Jun 2004
Hsieh Yao-Yuan, Chang Chi-Chen, Tsai Fuu-Jen, Yeh Lian-Shun, Lin Cheng-Chieh, Peng Ching-Tien
Abstract excerpt
OBJECTIVE: To investigate whether vascular endothelial growth factor (VEGF) gene 5'-UTR-460 polymorphism could be used as a marker of susceptibility to endometriosis. STUDY DESIGN: Women were divided into 2 groups, endometriosis (n = 122) and nonendometriosis (n = 131). Polymorphisms for VEGF were detected by polymerase chain reaction and BstUI (New England Biolabs, Beverly, Massachusetts) restriction enzyme...
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