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Mutational, epigenetic and expressional analyses of caveolin-1 gene in cervical cancers.

International journal of oncology - 1 Sept 2003

Chan Te-Fu, Su Tsung-Hsien, Yeh Kun-Tu, Chang Jan-Yi, Lin Ting-Hsu, Chen Jui-Chang, Yuang Shyng-Shiou F, Chang Jan-Gowth

Abstract excerpt

Caveolin-1 (CAV-1) protein, an integral membrane protein of caveolae membranes, is highly expressed in terminally differentiated cells and down-regulated in cells transformed by human papilloma virus infection. It may also be involved in the tumorigenesis of cervical cancer. CAV-1 gene is regarded as a candidate for the tumor suppressor gene and it can be inactivated in several ways, including point mutations,...

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PMID: 12888893

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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