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Article

Altered hippocampal expression of neuropeptides in seizure-prone GALR1 knockout mice.

Epilepsia - 1 Aug 2003

Fetissov Sergueï O, Jacoby Arie S, Brumovsky Pablo R, Shine John, Iismaa Tiina P, Hökfelt Tomas

Abstract excerpt

PURPOSE: Mice carrying a deletion of the GALR1 galanin receptor have recently showed spontaneous seizure phenotype with 25% penetrance. To better understand the role of neuropeptides, which are known to undergo complex plasticity changes with development of epileptic seizures, we characterized their expression in the hippocampal formation in GALR1- knockout (-KO) mice with or without seizures and in wild-type...

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Source

Identifiers

PMID: 12887433
DOI: 10.1046/j.1528-1157.2003.51402.x

Genes

GALR1
NPY
CCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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