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Article

Absence of the Kilifi mutation in the rhinovirus-binding domain of ICAM-1 in a Caucasian population.

Genetic testing - 1 Jan 2003

Vijgen Leen, Van Essche Mark, Van Ranst Marc

Abstract excerpt

Human rhinoviruses (HRV), responsible for approximately 60% of the common colds, are divided into two groups, according to their receptor specificity. The major group of HRVs gains access to human cells by binding to the intercellular adhesion molecule-1 (ICAM-1), whereas HRVs of the minor group use members of the low-density lipoprotein receptor (LDLR) family for cell entry. Previous studies confirmed that the...

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Identifiers

PMID: 12885341
DOI: 10.1089/109065703322146885

Genes

LDLR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Absence of the Kilifi mutation in the rhinovirus-binding domain of ICAM-1 in a Caucasian population.PMID 12885341Read ↗

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Rhinoviral receptor discrimination: mutational changes in the canyon regions of human rhinovirus types 2 and 14 indicate a different site of interaction.Semantic proximity Read ↗

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Measuring soluble ICAM-1 in African populations.Semantic proximity Read ↗

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