Article
Induction of antigen specific cellular immunity by vaccination with peptides from MN/CA IX in renal cell carcinoma.
Oncology reports - 1 Jan 2000
Shimizu Kazuhiro, Uemura Hirotsugu, Yoshikawa Motoyoshi, Yoshida Katsunori, Hirao Yoshihiko, Iwashima Kumiko, Saga Shinsuke, Yoshikawa Kazuhiro
Abstract excerpt
We investigated the induction of the specific immunity for renal cell carcinomas (RCC) using MN/CA IX, a tumor-associated antigen frequently expressed in RCC. We have generated 9-mer peptide derived from MN/CA IX and examined the antigenicity as a vaccine to induce specific immunity for RCC. To use mouse syngeneic system, we transfected human MN/CA9 cDNA into RenCa and BALB-3T3 cells originally from BALB/c mouse,...
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