Article
Spatio-temporal analysis of gene expression during aging in Drosophila melanogaster.
Aging cell - 1 Oct 2002
Seroude Laurent, Brummel Ted, Kapahi Pankaj, Benzer Seymour
Abstract excerpt
The relationship between gene expression and the regulation of longevity is poorly understood. Previous studies focusing on microarray or tissue-specific changes in gene expression as a function of age have provided evidence that gene expression is a dynamic process which is regulated, even late in an organism's lifespan. Using the enhancer-trap technique, a systematic analysis of the spatio-temporal regulation...
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