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Article

Regulation of gene expression is preserved in aging Drosophila melanogaster.

Current biology : CB - 9 Apr 1998

Rogina B, Vaupel J W, Partridge L, Helfand S L

Abstract excerpt

Aging, and the deterioration of biological performance that characterizes it, are routinely assumed to be due to a progressive global loss of homeostasis and a general increase in dysregulation [1-4] . We tested this hypothesis directly by measuring age-specific variability in gene expression. Analysis of the transcriptional activity of six genes in various inbred lines of Drosophila melanogaster unexpectedly...

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PMID: 9550706
DOI: 10.1016/s0960-9822(98)70184-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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