Article
Cryptococcus neoformans hyperfilamentous strain is hypervirulent in a murine model of cryptococcal meningoencephalitis.
PloS one - 1 Jan 2014
Feretzaki Marianna, Hardison Sarah E, Wormley Floyd L, Heitman Joseph
Abstract excerpt
Cryptococcus neoformans is a human fungal pathogen that causes lethal infections of the lung and central nervous system in immunocompromised individuals. C. neoformans has a defined bipolar sexual life cycle with a and α mating types. During the sexual cycle, which can occur between cells of oppo...
Topics
- Animals
- Cryptococcus neoformans
- Cytokines
- Disease Models, Animal
- Disease Progression
- Eosinophils
- Female
- Goblet Cells
- Meningitis, Cryptococcal
- Meningoencephalitis
- Mice
- Phenotype
- Serogroup
- Th2 Cells
- Virulence
- Virulence Factors