Article
Evidence for a chromosome 2p13-14 schizophrenia susceptibility locus in families from Palau, Micronesia.
Molecular psychiatry - 1 Nov 1998
Coon H, Myles-Worsley M, Tiobech J, Hoff M, Rosenthal J, Bennett P, Reimherr F, Wender P, Dale P, Polloi A, Byerley W
Abstract excerpt
A large multiplex schizophrenia pedigree ascertained from the Micronesian nation of Palau was genotyped with 406 microsatellite DNA markers evenly distributed throughout the genome. Assuming autosomal dominant inheritance, the highest genome-wide lod scores were found for DNA loci mapping to 2p13...
Topics
- Adult
- Age of Onset
- Chromosome Mapping
- Chromosomes, Human, Pair 2
- Female
- Follow-Up Studies
- Genes, Dominant
- Genetic Linkage
- Genetic Markers
- Genetic Predisposition to Disease
- Humans
- Lod Score
- Male
- Micronesia
- Pedigree