Article
Use of the tetracycline system for inducible protein synthesis in the kidney.
Journal of the American Society of Nephrology : JASN - 1 Aug 2003
Gallagher Anna Rachel, Schönig Kai, Brown Nelson, Bujard Hermann, Witzgall Ralph
Abstract excerpt
The great advantage of the tetracycline-inducible system lies in its ability to address a large variety of biological questions in a time-dependent and tissue-specific manner. This study describes a transgenic mouse line, rTA(LAP)-1, which produces the reverse tetracycline transactivator under control of the liver activator protein (LAP) promoter. Two reporter lines with luciferase and LacZ reporter genes were...
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