Article
Theoretical studies on solvation contribution to the thermodynamic stability of mutants of lysozyme T4.
Protein engineering - 1 Jun 2003
Deep Shashank, Ahluwalia J C
Abstract excerpt
Atomic solvation parameters (ASPs) are widely used to estimate the solvation contribution to the thermodynamic stability of proteins as well as the free energy of association for protein-ligand complexes. In view of discrepancies in the results of free energies of solvation of folding for various proteins obtained using different atomic solvation parameter sets, systematic studies have been carried out for the...
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